Introducing our team in the field of chemical biology and drug discovery, where we specialize in molecular sensors for quantitative optical imaging of cellular processes. With a primary focus on lipid-targeting drugs for cancer and neurodegenerative diseases, we delve into the pivotal roles of membrane lipids and lipid binding proteins in cancer, aging, and neurodegenerative diseases. Through our groundbreaking research, we aim to uncover the intricate ways in which lipids function within the cell and utilize this knowledge to develop novel lipid-targeting drugs for various human diseases.